Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

Machines running on human energy? Yes, it can happen, according to Dan Nicolau, Jr. from the Department of Integrative Biology at the University of California. Nicolau and his colleagues successfully ...

Adenosine is a short-acting endogenous molecule that is a purine nucleoside. The half-life is 6 seconds. Adenosine receptor activation results in multiple different actions depending on the location.

Adenosine kinase is an important enzyme that regulates both the intracellular and extracellular concentrations of adenosine. The inhibition of this enzyme has numerous clinical applications ranging ...

In the ED, adenosine is used to terminate supraventricular tachycardias (SVTs). It is also used by cardiologists for pharmacologic stress testing. Paroxysmal SVT has a prevalence of around 2.25 per ...

When cell mitochondria are exposed to electron-transport-chain poisons such as rotenone, the chemical-energy-producing organelles reboot themselves. First, mitochondria reorganize their valuable ...