Mitochondrial protein ALDH4A1 has been identified as an autoantigen implicated in atherosclerosis. A study published this month in the journal Nature highlights how the identification of this marker ...
In autoimmune diseases, a person’s immune system goes awry, developing antibodies to attack native proteins rather than foreign invaders. A novel chemical approach now makes it easier to discover the ...
Antigen microarrays hold great promise for profiling the humoral immune response in the settings of autoimmunity, allergy and cancer. This approach involves immobilizing antigens on a slide surface ...
The generation of anti-citrullinated protein autoantibodies (ACPA) are known key drivers in the pathogenesis of rheumatoid arthritis (RA) and are generated by peptidyl arginine deiminases (PADs), ...