IT is well established that an increase in the intracellular concentration of ionized calcium after excitation in the membrane is the key factor for initiation of contraction of various types of ...

Isolated cardiac myocytes exhibit spontaneous patterns of rhythmic contraction, driven by intracellular calcium waves. In order to study the coupling between spatio-temporal calcium dynamics and cell ...

Perhaps no cell type uses calcium in as many ways as does a cardiac myocyte. In addition to its well-known involvement in regulating cardiac contractility, recent studies have emphasized the ...

Researchers have discovered that a specific type of calcium channel -- a pore-like protein that nestles in the cell membrane and controls the flow of calcium into the cell -- regulates the relaxation ...

The coronary artery supplies blood to the heart. If calcium builds up in the coronary artery, it can lead to coronary artery disease and increase a person’s risk of a heart attack. Calcium is the most ...

Angela Ryan Lee, MD, FACC, is a board-certified cardiology and internal medicine physician. She also holds board certifications from the American Society of Nuclear Cardiology and the National Board ...