Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

HP1γ interacts with TRIM66 through the PxVxL motif: Crystal structure analysis and binding affinity studies demonstrate a specific interaction between the chromo shadow domain (CSD) of HP1γ and the ...

A number of large, multisubunit complexes have been identified by their ability to remodel chromatin. In the November 14 Sciencexpress, two reports describe an unexpected link between inositol ...

Our cells are usually frantically working to sustain life. Part of this work includes dividing, a process that creates more cells to support our growth when we are children or to replace old, worn-out ...

In eukaryotic cells, nucleosomes—composed of histone octamers—address the topological challenge of DNA packaging by condensing the DNA within the nucleus., crucial for genetic information storage and ...