Methods have been developed in the past to assess spontaneous and induced chromosomal aneuploidy in germ cells and in early pre- and postimplantation mammalian embryos. Some of these methods yield ...

A new study has addressed chromosomal imbalance in embryos, a condition that is currently the major cause of pregnancy loss in IVF. Joint research between the University of Kent's Professor Darren ...

As more people start families later in life, understanding the risks associated with late pregnancies has become increasingly important. Chromosomal abnormalities are genetic disorders resulting from ...

Chromosomal problems in children are more prevalent among late pregnancies primarily due to the age-related decline in egg and sperm quality and the increased risk of genetic mutations and ...

The development of chromosomal structural abnormalities, also known as gross chromosomal rearrangements (GCR), is essentially dependent on two distinct processes: double-strand breaks (DSB) and DSB ...

With the advent of engineered minichromosome technology in plants, an understanding of the properties of small chromosomes is desirable. Twenty-two minichromosomes of related origin but varying in ...

Turner syndrome (TS) is a genetic disorder caused by the partial or complete absence of one X chromosome. This is called monosomy and is typically caused by chromosomal nondisjunction. It is a very ...

Changes in either chromosome structure or number can occur during cell division. Each human has 46 chromosomes, 22 pairs of autosomes and 1 pair of sex chromosomes (XX: female or XY: male). During ...

Chromosome nondisjunction lands a heavy blow on the chin of humanity. The improper segregation of chromosomes during meiosis leads to chromosomally unbalanced eggs or sperm. If these gametes ...