DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

In a recent study published in the journal Nature Biotechnology, researchers in Switzerland used base and prime editing to create and analyze a wide array of variants of the epithelial growth factor ...

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

As we age, our cells accumulate DNA mutations. If any of these mutations confer a growth advantage to a self-renewing or long-lived progenitor cell, its lineage can expand. The progenitor cells that ...