Ongoing research suggests that an accumulation of toxic reactive oxygen species (ROS) in the area of the brain known as the hippocampal dentate gyrus may begin early on in patients with Alzheimer’s ...

Our brains can distinguish highly similar patterns, thanks to a process called pattern separation. How exactly our brains separate patterns is, however, not full,y understood yet. Using a full-scale ...

The dentate gyrus is distinct from the entorhinal cortex, the hippocampal region affected in early-stage Alzheimer's disease. Previous work, including by the laboratory of senior author Scott A. Small ...