The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer.
AptaFluor SAH Methyltransferase Assay is a high-throughput enzymatic assay for SAM-dependent methyltransferases. The assay uses a naturally existing SAH-sensing RNA aptamer, or riboswitch, which binds ...
(a) Overall Structure of Amuc_1547. (b) Magnesium Ion Binding Pocket in Amuc_1547 (PDB ID: 8HLS): The magnesium ion binding pocket is highlighted, featuring key loop regions (residues 285-304, 209-213 ...
The Metabolic Disease Laboratory provides services for the diagnosis of lysosomal storage diseases. The laboratory provides screening of urine for glycosaminoglycans, oligosaccharides, sialic acid, ...
Matthias Trost (left) is a Professor at Newcastle University (UK) with a lab comprising three focuses: method development for proteomics, the application of mass spectrometry in drug discovery and the ...
The COVID-19 pandemic and geopolitical conflict in Eastern Europe have done irreparable damage to the underpinnings of the clinical diagnostic industry. These events significantly impacted the supply ...