"Taken together the interplay of sex-specific gene regulation and its impact on ECM-related genes, influenced by factors such as genetics, epigenetics, environmental exposures, steroid hormones, aging ...

Charles Burger, MD: Pulmonary hypertension really refers to a state where the right heart is generating high pressures to circulate the blood through the lung. Pulmonary arterial hypertension is a ...

Erdosteine is a multimechanism, mucolytic agent that decreases the sputum viscoelastic properties and bacterial adhesion to the cell membrane, endowed with bronchial anti-inflammatory activity and a ...

Pulmonary arterial hypertension (PAH) is a devastating disease characterized by arteriopathy in the small to medium-sized distal pulmonary arteries, often accompanied by infiltration of inflammatory ...

Moderate to severe chronic obstructive pulmonary disease (COPD) may be an auto-immunity problem, according to researchers in Spain, who studied the presence of auto-antibodies in patients with COPD ...

—Investigators from the U.S. and U.K have identified neutrophil elastase (NE) and its inhibitor elafin as possible biomarkers in the pathogenesis of pulmonary arterial hypertension (PAH). “An ...

Alterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great potential as early ...

Further investigation on the pathogenesis and treatment of patients with schistosome-associated pulmonary arterial hypertension (Sch-PAH) may lead to improved symptoms and higher rates of survival. A ...

Researchers at Weill Cornell Medicine and New York-Presbyterian in New York have discovered that injecting mice with healthy pulmonary endothelial cells (ECs)—the cells that line the walls of blood ...

Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells-the cells that line the walls of blood vessels in the ...