A new study from Aarhus University shows that our cells' ability to clean out old protein clumps, known as aggregates, also includes a—up till now unknown—partnership with an engine that breaks down ...

Electron spin on magnetized surfaces affects how amyloid proteins form fibrils, revealing a new physical factor that could help control Alzheimer's-related aggregation. (Nanowerk News) A new study has ...

Protein-based therapeutics have transformed treatments for numerous diseases, yet their production remains highly complex and cost-intensive [1][2],[3][4]. Downstream processing (DSP), including ...

Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...

PTIR calculates the rates at which originally monomeric proteins are transformed into aggregates at various temperatures under initial-rate settings. Utilizing SMSLS for identical conditions generates ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Stressful environments often lead to protein unfolding and the formation of cytotoxic aggregates that can compromise cell survival. The molecular chaperone heat shock protein (HSP) 101 is a protein ...

Scientists at the Utrecht University in the Netherlands say they have identified a new way in which the toxic protein aggregates associated with Huntington’s disease may damage nerve cells and cause ...