Many diseases arise from the misplacement of proteins in cells. A potential solution to this problem has been developed: small molecules that help displaced proteins catch a ride with other proteins ...
9don MSN
Boosting the cell's own cleanup: New class of small molecules accelerate natural protein degradation
Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...
Experts have developed a breakthrough small-molecule drug, a 'protein degrader'. This molecule, called ACBI3, could potentially lead to new therapies independent of KRAS mutation type, improving ...
Jia’s team developed a protocol to improve the screening of protein pockets. This involved identifying the pockets, removing ...
HOUSTON & MILAN--(BUSINESS WIRE)--Sibylla Biotech and The University of Texas MD Anderson Cancer Center today announced a strategic collaboration agreement to discover and develop novel small-molecule ...
To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the ...
The researchers in this study tested the effects of a small molecule targeting the peroxisome proliferator-activated receptor gamma coactivator 1- α (PGC-1 α), a protein found in fat tissue that plays ...
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Small protein, big impact: Insights into how bacteria stabilize a key outer membrane complex
Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria. Their formidable defensive capabilities stem ...
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