For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of ...

Physical reservoir computing (PRC) utilizing synaptic devices shows significant promise for edge AI. Researchers from the Tokyo University of Science have introduced a novel self-powered ...

This valuable study links psychological theories of chunking with a physiological implementation based on short-term synaptic plasticity and synaptic augmentation. The theoretical derivation for ...

Calcium alpha-ketoglutarate, a naturally occurring metabolite, can restore key memory-related brain functions that have been disrupted in Alzheimer’s disease.

Psychedelics activate the 5-HT2A receptor, upregulate brain-derived neurotrophic factor, and enhance synaptic plasticity, leading to therapeutic potential for stress and psychiatric disorders. Credit ...

New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song, or directions to a friend’s house become encoded in our brains? The broad answer is that our brains undergo ...

Synaptic structure and function in WT, SAPAP3 KO, and psilocybin-treated SAPAP3 KO mice. (A) Wild-type (WT) mice: At the presynaptic terminal, action potentials open voltage gated calcium channels ...