Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, ...

Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...

In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR ...

Drug-delivering aptamers that can precisely target leukemia stem cells with enhanced potency have been developed. Delivering anticancer drugs with specificity and potency to cancer stem cells is an ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...

In 2021, the lab of chemical biologist and Nobel Laureate Carolyn Bertozzi, PhD, professor at Stanford University, characterized a new type of cell-surface protein, termed glycoRNAs, that form highly ...