“[...] here we reveal a link between short telomere length in ATII cells and post-viral lung fibrosis outcome in post-COVID-19 patients.” Lung injury is a ...
In a recent study published in The Journal of Infectious Diseases, researchers examined the response of alveolar type II (ATII) pneumocytes to tumor necrosis factor alpha (TNF-α) and Bruton tyrosine ...
A novel iPSC-derived lung-on-chip model mimics human alveolar tissue, revealing macrophage-driven tuberculosis responses.
Background: Krebs von den Lungen-6 (KL-6), predominantly expressed by type II alveolar cells, is linked to the prognosis and severity of interstitial lung disease (ILD). This investigation sought to ...
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First human 'lung-on-chip' model developed using stem cells from a single donor
Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.
The chip can simulate breathing and lung disease for an individual, holding promise for testing personalized treatments for tuberculosis.
Lung-on-chip model made of cells derived from a single person furthers understanding of tuberculosis and potential ...
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