This important study builds on previous work from the same authors to present a conceptually distinct workflow for cryo-EM reconstruction that uses 2D template matching to enable high-resolution ...

Researchers use cryo-EM and optical tweezers to investigate how an antiviral interacts with the herpes simplex virus.

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, ...

Surface model of SpCas9–reverse transcriptase–pegRNA–target DNA complex. The prime editor, composed of a SpCas9 and a reverse transcriptase, reverse transcribes template sequence in pegRNA, resulting ...

Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on the resolved structure of the NiV polymerase L-P ...

Treeline Biosciences is shaking things up in the world of drug discovery. They’re using some really advanced ways to look at ...

If you've ever accidentally sliced yourself on a broken glass or a piece of paper, you may have noticed that the bleeding can be hard to stop. Scientists have long wondered how the cascade of events ...

Research captures how the GRP94 protein shields itself to make sure it forms properly and suggests a way to target it for future disease treatments. Proteins are often called the building blocks of ...

Most people have witnessed -- or rather smelled -- when a protein enzyme called sulfite reductase works its magic. This enzyme catalyzes the chemical reduction of sulfite to hydrogen sulfide. Hydrogen ...

FairJourney Bio (FJBio), a leading global provider of antibody discovery and development services, today announced the ...