The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose intimate folds govern the destiny of cells. A mapping of ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Engineers have turned one of nature’s most reviled body parts into a precision tool, using the hollow feeding tubes of dead ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

3D cell cultures are no longer a futuristic idea. They’re already reshaping how we study diseases like cancer, offering more realistic models of how cells behave in the body. But despite their ...

Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced a ...

Cell division is the process of a cell splitting into two genetically identical daughter cells. The actin protein seen in this video is essential for successful cell division. While actin has several ...

The CellTiter-Glo ® 3D Cell Viability Assay is tailored to assess cell viability within 3D microtissue spheroids. Its reagent effectively permeates large spheroids and possesses enhanced lytic ...