Protein 'dark energy' provides insight into form vs. function in structure

Astronomers use the term dark energy to refer to energy in the universe that is unaccounted for by ordinary matter but ...
Business Wire

OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs

DAVIS, Calif.--(BUSINESS WIRE)--The OpenFold Consortium, a leading nonprofit artificial intelligence (AI) research consortium, today announced a preview release of OpenFold3, an open-source deep ...
TMCnet

OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs

The OpenFold Consortium, a leading nonprofit artificial intelligence (AI) research consortium, today announced a preview release of OpenFold3, an open-source deep learning model that predicts ...
Morningstar

OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs

Fully open source model accurately predicts the 3D structures of proteins and biomolecules in silico, and serves as a foundational model for next generation of cutting-edge Protein AI tools The ...
Frontiers

Small nucleic acid drugs-the dawn of functional cure of chronic hepatitis B

Chronic hepatitis B (CHB), a chronic liver infectious disease, results from persistent hepatitis B virus (HBV) infection lasting over 6 months. It has become a substantial global public health burden.
Scientific Research Publishing

Watson, J.D. and Crick, F.H.C. (1953) Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid. Nature, 171, 737-738.

ABSTRACT: DNA, deoxyribonucleic acid, carrying encoded genetic information at molecular level, is the most significant discovery in the history of genetics. Previous researches on DNA included topics ...
mccormick.northwestern.edu

CRISPR’s Efficiency Triples with Spherical Nucleic Acid Delivery System

CRISPR has the power to correct genetic mutations, but current delivery methods are either unsafe or inefficient, keeping the technology from reaching its full medical potential. With the power to ...
FiercePharma

CDMO BioSpring beefs up nucleic acid production with new API plant

German CDMO BioSpring is building a new production facility that it hopes will become one of the world's biggest manufacturing sites for DNA- and RNA-based active pharmaceutical ingredients (API). The ...
C&EN

Introducing the PARCH Scale for Quantifying the Hydropathy of Nucleic Acids and Nucleic Acid–Protein Complexes

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Hydropathy studies have been extensively conducted for proteins, offering valuable ...
Scientific Research Publishing

Watson, J. D., & Crick, F. H. C. (1953). Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid. Nature, 171, 737-738.

ABSTRACT: Plato placed great importance on the natural number one. Plato stated that the three properties of Plato’s one are indivisible, invariable, and equal and that an ideal one has no physical ...
FierceBiotech

Eli Lilly unwraps $700M nucleic acid R&D center in Boston Seaport, opens doors to biotechs

Eli Lilly has opened a $700 million R&D center in the Boston Seaport, boosting its RNA and DNA research capabilities and expanding its biotech-hosting Gateway Labs to the East Coast for the first time ...
News Medical

60 years in the making: Nanoparticles revolutionize nucleotide delivery

A recent perspective article published in the journal Nature Reviews Drug Discovery discussed the evolution of lipid nanoparticles (LNPs) for nucleic acid delivery. The authors, Pieter Cullis, ...