The Marijuana Herald

Study: CBD Protects Newborn Brain Cells From Oxygen Deprivation by Blocking Ferroptosis Pathway

In a study being published in the March issue of Phytomedicine and published online ahead of print, CBD was found to protect ...
Le Lézard

CorriXR Therapeutics Announces Publication of Additional Preclinical Data Corroborating Ability of NRF2 Knockout to Restore Chemosensitivity in Solid Tumors

A new publication from CorriXR Therapeutics, an oncology focused biotherapeutics company developing genetic medicines to ...
YouTube on MSN

Omega-3 supplements don't work - with one exception

Paradox: Eating more dietary omega-3s is associated with superior cognitive longevity. But there is not a strong signal for the benefits of supplemental omega-3s. Why? And what should you do?
BioSpace

FDA Conditional Pathway Not Necessary, Rare Disease Experts Say, While Applauding Intent

This pathway could enable conditional authorization for medicines based on a “plausible mechanism,” even without a randomized, controlled clinical trial, which is often impossible to conduct due to ...
C&EN

Regio- and Stereoselective Synthesis of Nitro-fatty Acids as NRF2 Pathway Activators Working under Ambient or Hypoxic Conditions

Department of Chemical Biology, Faculty of Science, Palacky University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic Department of Chemical Biology, Faculty of Science, Palacky University, ...
Frontiers

Paeonol ameliorates ferroptosis and inflammation in chondrocytes through AMPK/Nrf2/GPX4 pathway

Introduction: Chondrocyte ferroptosis is an important component of the pathogenesis of osteoarthritis. Paeonol, the main pharmacologically active ingredient of the Paeonia suffruticosa Andrews, is a ...
Scientific Research Publishing

Luo, Y., He, Y., Wang, Y., Xu, Y. and Yang, L. (2023) Adipose-Derived Mesenchymal Stem Cell Exosomes Ameliorate Spinal Cord Injury in Rats by Activating the Nrf2/ ho-1 Pathway ...

ABSTRACT: One serious lesion to the central nervous system is spinal cord injury (SCI). Due to its intricate pathophysiological mechanisms and the irreparability of nerve cells, conventional ...