In contrast, substances that bind directly to an enzyme's active site or the binding site of the endogenous ligand of a receptor are called orthosteric regulators or modulators. The site to which …

“Allosteric” was first introduced to mean the other site (i.e., a site distinct from the active or orthosteric site), an adjective for “regulation” to imply a regulatory outcome resulting from ligand binding at …

The meaning of ALLOSTERIC is of, relating to, undergoing, or being a change in the shape and activity of a protein (such as an enzyme) that results from combination with another substance at a point …

Define allosterism and distinguish between allosteric binding at orthosteric versus allosteric sites. Explain how environmental factors (ligands, substrates, ions, and other effectors) influence protein …

Allosteric regulation is a process by which the activity of a protein or enzyme is modulated by the binding of an effector molecule at a site other than the active site, known as the allosteric site.

Jul 26, 2025 · Allosteric regulation is a biological mechanism that controls protein activity, often enzymes, through the binding of molecules at a site distinct from the active site. This process is …

Allosteric regulation is classically defined as action at a distance, where a perturbation outside of a protein active site affects function.

In this article, we will learn about allosteric regulation, including allosteric inhibition and allosteric activation, and see examples.

Allosteric control, in enzymology, inhibition or activation of an enzyme by a small regulatory molecule that interacts at a site (allosteric site) other than the active site (at which catalytic activity occurs).

An allosteric or regulatory site is a place where the effectors bind and they may function as the allosteric activators or inhibitors. We can call effectors the modulators because they alter the enzyme’s …