The glucose transporter of erythrocytes (called GLUT1 to distinguish it from related glucose transporters in other tissues) is a type III integral protein with 12 hydrophobic segments, each of which is believed …

Transport of glucose is carried out by transporter proteins, among this GLUT1 is ubiquitously present and overexpressed in transformed cells. GLUT1 plays a vital role both in physiology and pathology.

GLUT1 is defined as a member of the GLUT/solute carrier family 2 (SLC2A), specifically categorized within Class I transporters, which facilitates the transport of hexoses across cell membranes down …

Jan 10, 2026 · Background Glucose transporter 1 (GLUT1) is a key protein for transmembranous glucose uptake of cells which is often overexpressed in cancer. Methods To better comprehend the …

Jun 21, 2025 · GLUT1 is widespread and responsible for continuous, basal glucose uptake in most cell types. It is highly concentrated in red blood cells and the blood-brain barrier, ensuring these areas …

Jun 11, 2025 · Glucose transporter isoform 1, GLUT1, is a member of a family of glucose transporters that facilitate the bidirectional transfer of substrates across cell membranes, particularly glucose.

Translocation of d -glucose across the BBB is mainly mediated by the high-affinity transporter GLUT1 that is highly expressed in the luminal and abluminal membranes of the endothelial cells (Fig. 1).

GLUT1 expression is upregulated in many tumors. Is a bidirectional transporter, allowing glucose to flow in 2 directions. Is expressed by renal tubular cells, liver cells and pancreatic beta cells. It is also …

Dec 20, 2023 · The Glut1 protein, encoded by the Glut1 gene, is a glucose transporter that facilitates the transport of glucose across cell membranes. Understanding the Glut1 gene is of utmost importance …

Aug 4, 2025 · GLUT1, also known as SLC2A1, plays a significant role in maintaining glucose uptake in all cells. It transports glucose across cell membranes through facilitated diffusion, a process that …