Dec 10, 2025 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood …

Sep 30, 2024 · Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments. Bone marrow …

Aug 20, 2024 · Who can get sickle cell disease? Sickle cell disease is a genetic disorder caused by mutations in hemoglobin genes, leading to a faulty hemoglobin protein, called hemoglobin S. …

Sep 9, 2024 · If you do not know whether you have sickle cell trait or disease, you can get a blood test. Blood tests can determine if your body makes the hemoglobin S protein and how much. Genetic …

Aug 22, 2024 · Sickle cell disease can cause pain, infections, and joint problems throughout the body. It can also lead to severe anemia and complications in specific body parts.

Managing Pain With Sickle Cell Disease People with sickle cell disease (SCD) may experience pain in different ways. The sickled cells that give the disease its name can lead to pain throughout the body …

We Perform Research The NHLBI Division of Intramural Research and its Hematology Branch, Sickle Cell Branch, and Sickle Cell Program include investigators who are actively engaged in research on …

People who have sickle cell disease inherit two abnormal hemoglobin genes, one from each parent. In all types of sickle cell disease, at least one of the two abnormal genes causes a person’s body to …

Aug 22, 2024 · Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent, and a normal hemoglobin gene from the other parent. People who have sickle cell …

SICKLE CELL DISEASE Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. People with SCD are born with it. This disease gets its name from the abnormal …