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Structure of cell death protein BAX

YouTubeWEHImovies

Structure of cell death protein BAX

Structural biology has revealed how the BAX protein is activated. The blue and yellow region shows where BH3-only proteins transiently bind BAX to release its 'tail' (red) that anchors BAX into mitochondrial membrane. This research helped to reveal how the transient ‘hit-and-run’ interaction between BAX and BH3-only proteins could be an ...

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